Questions?

Waiting is hard! Due to demand, we can completely sell out before our next round of stock reaches our fulfilment centre. If this happens, we will put the supplements in process up for pre-order before they’ve arrived. We track when our stock is due to arrive. Unless there is a supply problem outside our control, all orders will then be shipped out to our customers on that date. This allows our customers to reserve their supplements and be first in when they are restocked.

Pre-order times are subject to change based on supply chain but you will be updated.

Yay! Now you’ve made an order and you’re on your way to great gut health, now what?

Please allow up to 48 hours for our team to pick and pack your order. All orders are sent when all items are ready in full – this means that if you have a pre-order item in your order, all items will wait until that latest item is available and then will be sent out at the same time. Once packed, allow 2-8 business days in the USA where our stock is, or 10-14 days international.

As soon as your order is sent you will receive a shipping confirmation email from us.

*Please note: all shipping timeframes are from the advertised date of dispatch.

Standard and international shipping is free on all orders over $150USD.

For orders under $150USD standard shipping is $9.99 for USA and $14.99 for all other countries.

• Shipping options are available at check out. These include Express Shipping so you can get your order even FASTER!

Yay, time to celebrate – it’s on its way!

We will send you a shipping confirmation email which will have a ‘Track Order’ button site so you can follow the live tracking updates!

Your order may be on pre-order, as confirmed on the website at time of purchase. Be sure to check your original order confirmation, you won’t receive a shipping confirmation email until that pre-order date.

Think your order might be lost in transit? Although our carrier quote us 2-8 business days in the USA or 10-14 business days international sometimes things happen.

If your order isn’t delivered within 20 days, please contact us and we can launch an investigation.

*Please note: While we understand delays are frustrating, we are required to work within our carriers processes. If 20 days has passed we will investigate on your behalf to try and resolve any issues ASAP.

Provided your order has not shipped, please send us the new details and we can change this over for you.

*Please note: We can only send your order to the address you provide on your order – if you have provided an incorrect address, and the package is delivered there, we are unable to retrieve it so please check your address carefully!

We can ship to nearly every country.

FixBIOME’s instructions to our carriers is, where possible, to include all shipping costs in shipping, and there are usually no fees to pay.
However we do not cover personal import fees imposed at the boarder in local countries. This is the responsibility of the individual.  We sell globally and advise all customers to check their local import laws. This is outside the control of FixBIOME.

FixBIOME usually ships from Australia and the USA to make sure no matter where you are in the world we can get your package to you.

After a restock if you’re on our waitlist and shop the day of, all items will be shipped from the USA until we restock our Australian wharehouses.

You will receive free complementary international shipping on us.

Standard international shipping times apply unless express is purchased at checkout.

If you provide an unsecure address for delivery and do not purchase insurance at checkout and the courier shows package delivered with photo evidence – you will be responsible for your replacement.

Prices are displayed in your local currency anywhere you are in the world.

Due to health regulations, unfortunately we cannot accept the return of any of our dietary supplement products because you have simply changed your mind. Please ensure that any Product you select is right for you, based on the advice received from your healthcare provider or general practitioner and choose carefully.

Where required (under Australian Consumer Law and USA comparable legislation), FixBIOME will accept product returns and provide you with an exchange, repair or refund (as applicable) where:

• The product is damaged, or
• The product is faulty, and
• You can present your online tax invoice or other adequate proof of purchase.

FixBIOME may elect to return the product to the manufacturer to determine the nature of the problem.

FixBIOME Vitamins reserves the right not to offer an exchange, refund or repair where the item fault is a result of misuse or neglect.

Our products come with guarantees that cannot be excluded under the Australian Consumer Law. You are entitled to a replacement or refund for a major failure of the product. This extends to all our customers.

Products Fix No1 – Motility and Fix No2 – Control when used together were created for SIBO and other overgrowth. These formulations include biofilm busting ingredients and make for a powerful duo.

For SIBO Fix No1 – Motility, should be taken 3 times a day (with each meal) not 2 times a day as directed on the bottle for general gut health. Fix No2 should be taken one at morning and one at night with food.

We highly advise taking Gut Fix – Repair at the same time. The ingredients included are clinically researched to help restore the gut lining structural integrity that is often damaged during SIBO.

When you have SIBO, your small intestine faces constant stretching caused by the gas production of the overgrowth. This can cause the tight junctions to become lose and not function properly making relapse more likely and leading to other symptoms.

You can shop all 3 here: IBS Half Course

For candida we advise Fix No1 – Motility and Fix No2 – Control.

You can shop them in a bundle here: IBS 1 and 2 Top Up

For leaky gut we advise Gut Fix – Repair.

Gut fix takes a 3 pronged science based approach to addressing leaky gut from in inside out.

Gut Fix – Repair is a great product for those wanting to improve their overall gut health as it enhances many key functions needed for health digestion.

Gut Fix – Repair was designed to enhance your guts ability to extract vital nutrients from the foods and vitamins you eat.

There is no reason you cannot open the capsules and take them but exercise care in doing so.

We highly advise mixing them into a drink or smoothie with some health fats or taking them with a shot of water at the very least. Do not directly just take the oil into your mouth as it may sting.

These are powerful active ingredients, and you should exercise caution when opening the capsule not to get them in your eyes.

Do not place directly on your tongue or touch your eyes after handling.

P.S. They don’t taste great so try to mix them with something yummy!

Fix No1 – Motility and Fix No2 – Control both contain some ingredients that studies suggest can be beneficial to getting rid of parasites in the literature but note there are many types of parasites and these are supplementary products.

These can also be purchased in a bundle: IBS 1 and 2 Top Up

Fix No2 – Control contains berberine and our propriety antimicrobial blend which work together to form a powerful combination with bio film busting ingredients to enhance the product.

When it comes to berberine specifically we pay careful attention to the quality of our active ingredients and how we source, process and encapsulate them.

When dealing with active components of nature and formulating them for the gut, there are multiple factors to consider.

These include the way the gut functions and considering things like stomach acid, the surface area of the GI tract, motility factors, size of the practicals used, quality of the sourcing, where the ingredient was sourced from and at what time of year and how it is encapsulated all to ensure the best quality product possible.

We consider all these factors and more when choosing how to formulate and what combinations of research backed ingredients could be enhanced by combing them.

Fix No1 – Motility was designed for motility issues.

Yes, all our products are gluten free.

Yes, all our gut supplements are GMO free.

Our products are made in our FDA certified Lab in the USA.

Our formulations are created based on the medical research by our team of researchers, doctors and formulation experts.

Here at FixBIOME we spend a significant amount of our time on product formulation and reviewing all the medical literature when it comes to ingredients.

You can read some of the studies we have reviewed here: Research

We have done our best to sort it into subcategories to make it easier to navigate.

These products like most gut supplements have not been tested for safety during pregnancy.

And, as always, we recommend reaching out to your physician, midwife, or other qualified healthcare practitioner before using any new product.

The safety and wellbeing of your baby is of the upmost importance to us so we would advise you NOT to take these without advice until post birth and congratulations from the team at FixBIOME <3

Unfortunately due to the health regulations in our industry we cannot accept the return of any of our supplement products due to change of mind or circumstance.

We ask that everyone choose carefully and ensure that any product you select is right for you at this time in your life, based on the advice received from your healthcare provider or general practitioner.

It is in violation of health regulations to resell this product even if returned unopened and thus this is now stock we must legally dispose of and cannot resell.

Yes,Fix No1 does have a scent.

We use very high quality oils and these do have a a scent even when encapsulated.

Yes. FixNo1, FixNo2 and Gut Fix are all taken at the same time AM and PM.

AM:
1 x FixNo1 softgel
1 x FixNo2 capsule
2 x Gut Fix capsule

Repeat the same each night.

For those with more severe gut issues, the dosage is as follows:

Morning:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Midday:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Night:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Morning:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Night:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Course duration 6-8 weeks without a break at the following dose:

Morning:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Night:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Next:
Drop down for 8 more weeks at only AM or PM dose. Three pack provided for this.

Continue with Gut Fix long-term.

10-14 weeks without a break at the following dose:

Morning:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Night:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

14-16 weeks at a dosage of:

Morning:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Midday:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

Night:
1x FixNo1 capsule
1x FixNo2 capsule
2x Gut Fix capsule

For those with mild gut issues (experience issues under 3 months), Gut Fix should be taken daily in the AM and PM.

If lifestyle factors, stress, illness or other event causes a re-flare, repeat the course.

Do not underestimate the mind-to-gut connection. It is important to manage stress. Stress affects the Migrating Motor Complex (MMC), which is essential in maintaining the gut’s health and keeping things in their newfound balance.

Often gut issues occur because of underlying issues that need daily support.

These usually stem from the MMC or issues with tight junction function.

The MMC is the sweeping motion that goes through your intestines every 90 minutes, keeps bacteria levels in check and helps move things through your gut, helping to keep you regular. FixNo1 and FixNo2 help support this mechanism.

The tight junctions are the ‘draw bridge’ barrier between your gut and the rest of the body that keeps the right things in and lets the right things out into the bloodstream (like nutrients). Gut Fix helps support this mechanism.

When this doesn’t function as it should and requires on-going support, which can happen due to a variety of issues (including injury/insult to the gut caused by food poisoning or illness in the past, immune conditions, history of eating disorders, medications, thyroid issues, certain medical conditions, surgery on the abdominal area) then daily support may be required.

FixNo1 and FixNo2 can be taken daily or as symptoms re-trigger to help support the MMC and keep things in check.

If a life/health event causes a re-trigger to repeat the course.

Gut Fix should be taken continuously daily AM and PM.

*Long-term users of FixNo1 and FixNo2 can contact customer service for 15% off exclusive to their account. Only eligible after 1 x 6 pack and one 3 pack minimum.

As with moderate, gut issues often occur because of underlying issues that need daily support.

Often gut issues occur because of underlying issues that need daily support.

These usually stem from the MMC (migrating motor complex) or issues with tight junction function. The MMC is the sweeping motion that goes through your intestines every 90 minutes, keeps bacteria levels in check, helps move things through your gut and helps to keep you regular. FixNo1 and FixNo2 work to support this mechanism.

The tight junctions are the ‘draw bridge’ barrier between your gut and the rest of the body that keeps the right this in and lets the right things out into the bloodstream (like nutrients). Gut Fix helps support this mechanism.

When this doesn’t function as it should and requires on-going support, which can happen due to a variety of issues (including injury/insult to the gut caused by food poisoning or illness in the past, immune conditions, history of eating disorders, medications, thyroid issues, certain medical conditions, surgery on the abdominal area) then daily support may be required.

FixNo1 and FixNo2 and Gut Fix can be taken continuously daily, AM and PM if symptoms return without it, or you can do another course in the event of a re-trigger.

*Long-term users of FixNo1 and FixNo2 can contact customer service for 15% off, exclusive to their account. Only eligible after purchase of 1 x 6 pack and one 3 pack minimum. Discount applied on all future orders of 2, 3 or 6 packs. Terms & Conditions apply.

Unfortunately, sometimes in life, things will happen that trigger a relapse.

Reasons can range from illness, antibiotic use, incorrect use of probiotics, infection, surgery, severe or stressful situations affecting the guts’ function, food poisoning, etc.

Reasons can also include failure to continue to support a damaged MMC with a lowered dose of FixNo1 and FixNo2 post-treatment when you required that, which allows things to build up over time.

Please don’t underestimate the impact of stress on the gut. Stress directly affects how our gut functions and stress management is an important factor in avoiding relapse. Stress takes blood flow away from the gut and redirects it to other parts of the body, allowing food and bacteria not to move along as well as it should. You can use FixNo1 and FixNo2 to help counteract this, but stress management is still vital in avoiding relapse.

In this case of relapse, restart the course and see our duration guidelines for use recommendations depending on the severity of gut issues that have come back.

*Long-term users of FixNo1 and FixNo2 can contact customer service for 15% off, exclusive to their account. Only eligible after purchase of 1 x 6 pack and one 3 pack minimum. Discount applied on all future orders of 2, 3 or 6 packs. Terms & Conditions apply.

1.Not supporting your guts MMC when it was required for you
2. Illness or infection
3. Underlying conditions affecting the gut
4. PPI use
5. Certain medications
6. Stress -which directly impacts how the gut function and keeps bacteria levels in check and things regular, allowing for build-up and dysbiosis to occur
7. Inappropriate use of probiotics
8. Antibiotic use
9. Disordered eating patterns

Yes, you can stay on FixNo1, FixNo2 and Gut Fix at the recommended or a lower dose if it benefits you/is required.

Some customers choose to stay on the full dose long-term. Every gut is different, and you should always talk to your healthcare provider about what is right for you.

Long-term users of the FixBIOME system can receive an exclusive code for 15% discount once they have purchased a minimum of 2 x IBS 6-8 Weeks Course (or the equivalent – so for example, if you have purchased 4 x IBS Half Course, or 2 x IBS Half Course and 1 x IBS 6-8 Weeks Course you would also qualify). Please reach out to hi@fixbiome.com if you qualify for this discount! Terms & Conditions apply.

Long-term users of the FixBIOME system can receive an exclusive code for 15% discount once they have purchased a minimum of 2 x IBS 6-8 Weeks Course (or the equivalent – so for example, if you have purchased 4 x IBS Half Course, or 2 x IBS Half Course and 1 x IBS 6-8 Weeks Course you would also qualify). Please reach out to hi@fixbiome.com if you qualify for this discount! Terms & Conditions apply.

Email hi@fixbiome.com and we will check you qualify and send you your custom code.

No, this is just for our loyal customers.

FixBIOME formulates all our products on the most up to date medical literature. We employ a team of doctors, and formulation experts with decades of experience to bring the best products to market.

Every ingredient in our supply chain is carefully checked to ensure it meets our strict quality standards before progressing to ingredient processing. We understand that when dealing with components of nature it MATTERS how we source, at what stage of the life cycle and what parts of the natural inclusion have been used. How ingredients are processed is also incredibly important to how they impact the gut so we apply a science based approach to this after our approval process.

Our team of health experts source each ingredient in our products with great care. Every ingredient must be traditionally used for its stated purpose or have scientific evidence to support its health claims.

Every ingredient in our supply chain is carefully checked to ensure it meets our strict quality standards before progressing to ingredient processing. We understand that when dealing with components of nature it MATTERS how we source, at what stage of the life cycle and what parts of the natural inclusion have been used. How ingredients are processed is also incredibly important to how they impact the gut so we apply a science based approach to this after our approval process.

Many antimicrobials are only as effective as the way and form they are processed in. We have dedicated great resources, research, and expertise in formulation optimisation.

Our core team consists of not only medical experts, but people who suffered with years of gut issues. We stand behind our products with passion after spending years trying to find solutions. We care about your gut health. We understand all the medical and psychological consequence of poor gut health and are frequently evaluating the growing body of medical literature.

FixBIOME was founded by Jasmine Chilcott after years of struggling with gut issues and reoccurring SIBO with no resolve from traditional western medicine.

Later, Co-Founder Dr James Freeman was brought on with years of experience in medicine. Dr Freeman has been published in some of the world’s leading Gastroenterology journals.

Yes, FixBIOME is a majority female owned and operated company.

Yes, our products are made in America in our FDA approved lab.

FixBIOME has offices in the USA (Los Angeles) and Australia (Sydney).

You can contact us with any questions at hi@fixbiome.com

FixBIOME is an Australian company, however we manufacture in the USA in our FDA compliant lab as we required processing and formulation methods that were not available in Australia.

FixBIOME formulates all our products on the most up to date medical literature. We employ a team of doctors, and formulation experts with decades of experience to bring the best products to market.

Every ingredient in our supply chain is carefully checked to ensure it meets our strict quality standards before progressing to ingredient processing. We understand that when dealing with components of nature it MATTERS how we source, at what stage of the life cycle and what parts of the natural inclusion have been used. How ingredients are processed is also incredibly important to how they impact the gut so we apply a science based approach to this after our approval process.

No – we use DGL licorice.
Unprocessed licorice root can raise blood pressure but the licorice we formulate with has had the component responsible for that effect removed. This is called deglycyrrhizinated licorice.

Red thyme has strong antimicrobial properties that can help kill off bacterial and fungal overgrowth when formulated in a way that ensures the delicate balance and stability of this powerful essential oil as in Fix No1 – Motility.

Research on red thyme for general gut health:

• The Potential Gastrointestinal Health Benefits of Thymus Vulgaris Essential Oil: A Review
• Antibacterial Activity of Thyme and Lavender Essential Oils
• The Potential Gastrointestinal Health Benefits of Thymus Vulgaris Essential Oil: A Review
• A Focused Insight into Thyme: Biological, Chemical, and Therapeutic Properties of an Indigenous Mediterranean Herb
• Thymol and Thyme Essential Oil—New Insights into Selected Therapeutic Applications

Research on red thyme for SIBO:

• Select Herbals Proposed as Beneficial in the Eradication of Small Intestinal Bacterial Overgrowth

Research on red thyme for IBS:

• Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome

We use oregano oil in Fix No1 – Motility as it has been found to have a broad antimicrobial spectrum effect that can work to reduce bacterial overgrowth in the gut. It may also benefit gut health by assisting in the restoration of the tight junctions in the intestines and has long been used in Chinese medicine. These junctions often become lose in individuals suffering from SIBO and Candida which can result in a condition called leaky gut.

Research on oregano oil for SIBO

• Essential Oils of Oregano: Biological Activity beyond Their Antimicrobial Properties
• Susceptibility and intrinsic tolerance of Pseudomonas aeruginosa to selected plant volatile compounds
• The Natural Antimicrobial Carvacrol Inhibits Campylobacter jejuni Motility and Infection of Epithelial Cells
• The antibacterial mechanism of carvacrol and thymol against Escherichia coli

Research on oregano oil for IBS:

• Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials

We include Sage leaf in Fix No1 – Motility because Sage leaf has anti-inflammatory properties and aids in smooth functioning of the digestive system. Sage has been used for treating intestinal cramps, flatulence, and indigestion for thousands of years in traditional Chinese medicine.

Research on sage leaf for general gut health:

• Chemistry, Pharmacology, and Medicinal Property of Sage (Salvia) to Prevent and Cure Illnesses such as Obesity, Diabetes, Depression, Dementia, Lupus, Autism, Heart Disease, and Cancer
• Medicinal Plant Leaf Extract from Sage and Lemon Verbena Promotes Intestinal Immunity and Barrier Function in Gilthead Seabream (Sparus aurata)

Research on sage leaf for IBS:

• Herbal medicines for the management of irritable bowel syndrome: A comprehensive review
• The Treatment of Irritable Bowel Syndrome
• Complementary and Alternative Medicine and Mind–Body Therapies for Treatment of Irritable Bowel Syndrome in Women
• Irritable Bowel Syndrome

We use lemon balm leaf in Fix No1 – Motility because lemon balm is gastro-protective, and its active ingredient that has anti-inflammatory effects and has been shown to improve digestive symptoms. Lemon balm helps reduce stress and brain fog promoting a stable mood and sense of wellbeing.

Research on lemon balm leaf for general gut health:

• Chemical composition and in vitro antimicrobial activity of essential oil of Melissa officinalis L. from Romania
• Basal and Spasmolytic Effects of a Hydroethanolic Leaf Extract of Melissa officinalis L. on Intestinal Motility: An Ex Vivo Study

Research on lemon balm leaf for SIBO:

• Herbal Therapies in Functional Gastrointestinal Disorders: A Narrative Review and Clinical Implication
• Investigation of the Antimicrobial activity of essential oils of culinary and medicinal herbs and spices against selected gastrointestinal pathogens
• Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome

Research on lemon balm leaf for IBS:

• The Protective Effect of Melissa officinalis L. in Visceral Hypersensitivity in Rat Using 2 Models of Acid-induced Colitis and Stress-induced Irritable Bowel Syndrome: A Possible Role of Nitric Oxide Pathway
• Treatment of irritable bowel syndrome with herbal preparations: results of a double-blind, randomized, placebo-controlled, multi-centre trial
• Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials
• Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome
• Combining Herbs in a Formula for Irritable Bowel Syndrome

We include peppermint oil for it’s multitude of effects on the gut. Our gut contains lots of smooth muscle tissue to ensure the healthy digestion of foods. Peppermint oil is a kind of antispasmodic used to relieve muscle spasms. It eases the symptoms such as cramping, bloating, and excessive farting (flatulence) and can reduce nausea.

Research on peppermint oil for general gut health:

• Peppermint oil effects on the gut microbiome in children with functional abdominal pain
• Peppermint Oil – Historical use case for IBS reduction
• Peppermint Oil – Historical use case for helping with digestive disorders

Research on peppermint oil for SIBO:

• Herbal Medicines for Gastrointestinal Disorders in Children and Adolescents: A Systematic Review
• The treatment of small intestinal bacterial overgrowth with enteric-coated peppermint oil: A case report

Research on peppermint oil for IBS:

• The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data
• Review article: The physiologic effects and safety of Peppermint Oil and its efficacy in irritable bowel syndrome and other functional disorders
• Peppermint Oil for the Treatment of Irritable Bowel Syndrome: Optimizing Therapeutic Strategies Using Targeted Delivery (PERSUADE)

We use and particle optimise berberine in Fix No2 – Control as berberine modulates the composition of the gastrointestinal microbiota. It can also limit gastrointestinal microbiota variety by affecting the relative concentrations of specific microbes in our digestive tracts.

Berberine has favourable effects on the intestinal immune cells and impacts the expression of multiple intestinal immunity components for SIBO treatment.

Here is our research to support our use of berberine.

Research on Berberine for general gut health:

• Effects of Berberine on the Gastrointestinal Microbiota
• Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)
• Berberine
• Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine
• Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study
• Berberine and probiotics supplementation decreases post-meal lipid spike in Type II diabetes patients – 12-week RCT

Research on Berberine SIBO:

• Eradication of small intestinal bacterial overgrowth in irritable bowel syndrome using herbal therapy: A case report

Research on Berberine IBS:

• Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats
• A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome
• Therapeutic Effects of Berberine Hydrochloride on Stress-Induced Diarrhea-Predominant Irritable Bowel Syndrome Rats by Inhibiting Neurotransmission in Colonic Smooth Muscle
• Berberine Improves Symptoms of Irritable Bowel Syndrome
• Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner
• Effect of berberine on irritable bowel syndrome: A symptom-based review

We include Chinese rhubarb root because it has been found to assist in restoring gut microbiota balance, restore disrupted flora, and prevent microbiota shift. Rhubarb has positive effects on intestinal immune activity and our gut makes up the largest portion of our immune system. Rhubarb is used for digestive issues such as constipation, diarrhoea, heartburn and stomach pain. Rhubarb is also an effective antimicrobial.

Chinese rhubarb root and rhizome for general gut health:

• A Systematic Review of Rhubarb (a Traditional Chinese Medicine) Used for the Treatment of Experimental Sepsis
• Rheum Officinale
• Potential Health Benefits of Rhubarb

Chinese rhubarb root and rhizome for SIBO:

• Proceedings of the 2017 2nd International Conference on Materials Science, Machinery and Energy Engineering (MSMEE 2017)

Chinese rhubarb root and rhizome for IBS:

• Management of Irritable Bowel Syndrome (IBS) in Adults: Conventional and Complementary/Alternative Approaches
• Advances in bio-active constituents, pharmacology and clinical applications of rhubarb
• Elucidating dosage-effect relationship of different efficacy of rhubarb in constipation model rats by factor analysis
• The diarrhoeogenic and antidiarrhoeal bidirectional effects of rhubarb and its potential mechanism

Indian barberry has potent antimicrobial activity against major gastrointestinal pathogens. Many people that suffer from gut issues have unhelpful overgrowths or imbalances of bacteria types or “bad bacteria” and research suggests Indian barberry root extract is a powerful counter.

Indian barberry root extract for general gut health:

• A quick overview on some aspects of endocrinological and therapeutic effects of Berberis vulgaris L.
• Berberis
• Effects of different forms of barberry root (Berberis vulgaris) on growth performance, muscle fatty acids profile, whole-body composition, and digestive enzymes of rainbow trout (Oncorhynchusmykiss)
• Anti-Inflammatory and Immunomodulatory Effects of Barberry (Berberis vulgaris) and Its Main Compounds

Indian Barberry root extract for IBS:

• Irritable bowel syndrome and diet
• Herbal medicines for the management of irritable bowel syndrome: A comprehensive review

Licorice root has antimicrobial properties. It also helps relieve symptoms of indigestion including acid reflux, upset stomach, and heartburn.
DGL licorice helps sooth your stomach lining and supports adrenal glands. The licorice we formulate with is deglycyrrhizinated (DGL). This means it has minimal effect on your blood pressure compared to regular licorice and is safer for long-term use.

DGL licorice supports:

• reduction in acid reflux
• mucus lining production in the stomach and intestines
• reduction in heart burn
• healing of ulcers
• reduction in bloating

DGL Licorice for general gut health:

• Glycyrrhiza glabra (Licorice)
• Glycyrrhiza Glabra Root
• Prevention of symptoms of gastric irritation (GERD) using two herbal formulas: An observational study

DGL Licorice for SIBO:

• An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study
• Prebiotic Potential of Herbal Medicines Used in Digestive Health and Disease

DGL Licorice for IBS:

• Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study

We use Chinese skullcap root as skullcap assists in calming and nourishing the nerve area of the digestive tract and reducing spasms, pain, and bloating safely and effectively.

Chinese skullcap root for general gut health:

• Scutellaria baicalensis
• Skullcap (Scutellaria baicalensis) Extract and Its Active Compound, Wogonin, Inhibit Ovalbumin-Induced Th2-Mediated Response
• Anti-inflammatory effect of wogonin on allergic responses in ovalbumin-induced allergic rhinitis in the mouse
• Anti-Inflammatory and Immunomodulatory Effects of Barberry (Berberis vulgaris) and Its Main Compounds

Chinese skullcap root for SIBO:

• Chinese herbal medicine for the treatment of small intestinal bacterial overgrowth (SIBO)

Chinese skullcap root for IBS:

• The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota
• Treatment of irritable bowel syndrome in China: A review
• Chinese Herbal Medicine for Irritable Bowel Syndrome: A Meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials

We use coptis root in Fix No2 – Control as it has been used to promote healthy digestive and microbial environments. Berberine alkaloids in coptis have been researched for their influence on microbes in the gut.

Coptis root and rhizome extract for general gut health:

• Coptidis Rhizoma: a comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and toxicology
• Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity

Coptis root and rhizome extract for SIBO:

• The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota

Coptis root and rhizome extract for IBS:

• Tracking evidences of Coptis chinensis for the treatment of inflammatory bowel disease from pharmacological, pharmacokinetic to clinical studies
• Antibacterial activities of Coptis chinensis and Glycyrrhiza glabra against seven bacteria associated with human gastrointestinal infections

We use ginger rhizome in Fix No2 – Control as it has been shown to help alleviate IBS and SIBO symptoms by protecting the stomach from oxidative stress-induced damage.

Ginger rhizome has been widely used in Chinese, Ayurvedic, Unani medicines for thousands of years for many ailments including pain, inflammation, and gastrointestinal disorders.

Ginger rhizome for general gut health:

• Herbs and Spices in the Treatment of Functional Gastrointestinal Disorders: A Review of Clinical Trials
• Ginger in gastrointestinal disorders: A systematic review of clinical trials
• Gut Microbiota Variation With Short-Term Intake of Ginger Juice on Human Health
• Ginger rhizomes (Zingiber officinale): A spice with multiple health beneficial potentials

Ginger rhizome for SIBO:

• Pharmacological Basis for the Medicinal Use of Ginger in Gastrointestinal Disorders

Ginger rhizome for IBS:

• Is ginger effective for the treatment of Irritable Bowel Syndrome? A double blind randomized trials
• Is ginger effective for the treatment of Irritable Bowel Syndrome? A double blind randomized controlled pilot trial
• Ginger relieves intestinal hypersensitivity of diarrhea predominant irritable bowel syndrome by inhibiting proinflammatory reaction

We use dill seed in Fix No2 – Control and it aids peristaltic action by eliminating wastes from the body, making it an effective constipation treatment. Additionally, the herb’s antacid characteristic reduces the creation of excessive acids in the stomach, which helps cure indigestion, ulcers, and gastritis while promoting improved nutritional absorption.

Dill seed for general gut health:

• The Study of Anti-Inflammatory Activity of Oil-Based Dill (Anethum graveolens L.) Extract Used Topically in Formalin-Induced Inflammation Male Rat Paw

• Dill

Dill seed for SIBO:

• Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome
• Select Herbals Proposed as Beneficial in the Eradication of Small Intestinal Bacterial Overgrowth

Dill seed for IBS:

• Combining Herbs in a Formula for Irritable Bowel Syndrome
• Efficacy and Safety of a Novel Herbal Medicine in the Treatment of Irritable Bowel Syndrome: A Randomized Double-Blinded Clinical Trial
• Herbal medicines for the management of irritable bowel syndrome: A comprehensive review

A lack of zinc is directly linked to damage of the gut membrane barrier. Studies have shown that zinc can assist in tightening a leaky gut.

Zinc also supports:

• immune system
• gut health
• gut lining
• thyroid function
• reduction in bloating
• skin health

Studies supporting the use of zinc for general gut health:

• Zinc and gastrointestinal disease
• Zinc and its importance for human health: An integrative review
• Effects of Dietary Zinc Sources on Growth Performance and Gut Health of Weaned Piglets

Studies supporting the use of zinc for SIBO:

• Chronic Dietary Zinc Deficiency Alters Gut Microbiota Composition and Function
• Effects of Iron and Zinc Biofortified Foods on Gut Microbiota In Vivo (Gallus gallus): A Systematic Review
• Small Intestinal Bacterial Overgrowth is Common in Chronic Pancreatitis (CP) and Associates with Diabetes, CP Severity, Low Zinc Levels and Opiate Use
• Gut Microbiota as a Mediator of Essential and Toxic Effects of Zinc in the Intestines and Other Tissues

Studies supporting the use of zinc for IBS:

• P0339 – Nutritional Deficiencies in Irritable Bowel Syndrome: A North American Population-Based Study
• Nutritional status in irritable bowel syndrome: A North American population‐based study
• Correlation Between Zinc Nutritional Status with Serum Zonulin and Gastrointestinal Symptoms in Diarrhea-Predominant Irritable Bowel Syndrome: A Case-Control Study
• Zinc Deficiency and Intestinal Permeability in the Context of Rational Diagnostic and Drug Development for Diarrhea-Predominant Irritable Bowel Syndrome
• The potential impact of nutritional intake on symptoms severity in patients with comorbid migraine and irritable bowel syndrome

We use super high quality L-glutamine as studies prove it helps, nourishes and supports gut cell regeneration which occurs every 48hrs. L-Glutamine is a major fuel source for enterocytes (intestinal cells and brain cells). L-glutamine is a unique amino acid that serves countless major functions in your body. L-glutamine has been widely studied and found to support gut health.

• supports muscle mass
• fuels the cells of the gut to function properly
• supports the integrity of the gut lining
• reduction in bloating

Studies to support the use of L-glutamine for general gut health:

• L-Glutamine Supplementation Improves the Benefits of Combined-Exercise Training on Oral Redox Balance and Inflammatory Status in Elderly Individuals
• Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation
• The role of glutamine in supporting gut health and neuropsychiatric factors

Studies to support the use of L-glutamine for SIBO:

• The Role of Glutamine in the Complex Interaction between Gut Microbiota and Health: A Narrative Review
• Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions

Studies to support the use of L-glutamine for IBS:

• Glutamine Supplementation Enhances the Effects of a Low FODMAP Diet in Irritable Bowel Syndrome Management
• Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome
• Glutamine for the Treatment of Patients With Irritable Bowel Syndrome (AT005291)
• Clinical effects and safety of Compound Glutamine Entersoluble Capsules for diarrhea-predominant irritable bowel syndrome: A systematic review and meta-analysis

We use marshmallow root in Gut Fix – Repair as it is a powerful ingredient. It has been studied and found to improve mucous membrane health.

Marshmallow root supports the gut by:

• coating the digestive tract with a protective lining to support a balanced inflammatory response in the gut
• restoring cell junctions
• soothing the stomach lining
• promoting regular bowel movements

Studies supporting the use of marshmallow root general gut health:

• Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon

Studies supporting the use of marshmallow root for SIBO:

• Aqueous extracts and polysaccharides from Marshmallow roots (Althea officinalis L.): Cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro
• Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders
• Eradication of small intestinal bacterial overgrowth in irritable bowel syndrome using herbal therapy: A case report

Studies supporting the use of marshmallow root for IBS:

• Herbal medicines for the management of irritable bowel syndrome: A comprehensive review
• Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study

We use quercetin in Gut Fix – Repair as quercetin can enhance intestinal barrier function and modulates gut microbiota composition. The activities of tight junction proteins at the gut epithelium enhance barrier functions and reduce inflammation, protecting the host from colonic diseases.

Quercetin is a naturally occurring free radical scavenger that supports healthy immune system function. Studies suggest that quercetin affects the progress of microbiota-associated diseases. Notably, quercetin supplementation increased gut microbial diversity, which may improve gut protection.

Studies supporting the use of quercetin for general gut health:

• Potential Implications of Citrulline and Quercetin on Gut Functioning of Monogastric Animals and Humans: A Comprehensive Review
• Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in Citrobacter rodentium-Infected Mice
• Dietary Quercetin Supplementation Attenuates Diarrhea and Intestinal Damage by Regulating Gut Microbiota in Weanling Piglets

Studies supporting the use of quercetin for SIBO:

• Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in Citrobacter rodentium-Infected Mice
• Alternative Treatment Approaches to Small Intestinal Bacterial Overgrowth: A Systematic Review

Studies supporting the use of quercetin for IBS:

• Natural polyphenols for the prevention of irritable bowel syndrome: molecular mechanisms and targets; a comprehensive review
• Quercetin Attenuates Visceral Hypersensitivity and 5-Hydroxytryptamine Availability in Postinflammatory Irritable Bowel Syndrome Rats: Role of Enterochromaffin Cells in the Colon
• Potential Implications of Citrulline and Quercetin on Gut Functioning of Monogastric Animals and Humans: A Comprehensive Review

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